Cancer Guide to Eye Cancers

Intraocular cancer is the official name for eye cancer.

How Does It Happen?

When healthy cells in your eye change -- or mutate -- and grow too quickly in a disorganized way, they can form a mass of tissue called a tumor. If these problem cells start in your eye, it's called intraocular cancer, or primary eye cancer. If they spread to your eye from another part of your body, it's called secondary eye cancer.

Eye cancer may lead to changes in vision.

Symptoms

The most common sign of eye cancer is a change in your vision. You may not be able to see well, or you might see flashes of light or spots (floaters). You also may notice a new dark spot in one eye or a change in its size or shape. But eye cancer doesn't always cause symptoms early on, and these things can happen for many other reasons.

The most common type of primary eye cancer is uveal melanoma.

Uveal Melanoma

This is the most common kind of primary eye cancer. It happens when cells form a tumor in a part of your eye called the uvea. It has three parts: the colored part of your eye called the iris, the ciliary body (it makes fluid and helps you focus), and the choroid layer that supplies blood to your eye. This layer is where the cells usually start to change and become cancerous.

Retinoblastoma is usually found in children before the age of 5.

Retinoblastoma

This is the most common type of eye cancer in children, but it's diagnosed in only 200 to 300 kids in the U.S. each year. It's usually found before age 5. It starts while a baby is in the womb, in the very back part of the eye called the retina. As the baby grows, cells called retinoblasts grow out of control and form a tumor. Sometimes it's first noticed in a picture, when one of the pupils looks different from the other.

Eye cancer may form in the lymphatic system of the eyes.

Intraocular Lymphoma

Your lymphatic system is made of lymph nodes -- glands that help you get rid of waste and germs. They're part of your immune system, and you have them all over your body, including your eyes. This rare kind of eye cancer starts in those lymph nodes. It can be hard to diagnose because the symptoms aren't the same for everyone.

Cancer may form in the conjunctiva that lines the outside of the eyeball.

Conjunctival Melanoma

The lining outside your eyeball and inside your eyelid is called the conjunctiva. This rare kind of cancer happens when a tumor grows in that lining -- it can look like dark spots on your eye. If it isn't found and treated quickly, it can spread to other parts of your body through your lymphatic system.

Cancer that starts in the tear ducts is called lacrimal gland cancer.

Lacrimal Gland Cancer

This rare type of cancer starts when a tumor forms in the glands that make tears. They're called lacrimal glands, and you have them under the upper eye lid of each eye. These tumors tend to happen more often in people who are in their 30s.

Eyelid cancer may form due to excess sun exposure.

Eyelid Cancer

This type of skin cancer shows up on or inside your eyelid. The most common form of it -- called basal cell carcinoma -- happens on your lower lid and is caused by spending too much time in the sun. People who have fair or pale skin are more likely to acquire it. Eyelid cancer can usually be treated easily and effectively if it's found early.

Certain types of cancers may start elsewhere and spread to the eye.

Secondary Eye Cancer

In most cases, cancer doesn't start in the eye -- it spreads there from somewhere else in your body. That's called secondary cancer, and it happens most often with breast cancer in women and lung cancer in men. It also can go to your eyes from your skin, kidney, colon, and thyroid, among other places.

Physical exam, biopsy and lab tests may be used to diagnose eye cancer.

Diagnosis

Your doctor will ask about your symptoms and check your vision and the way your eyes move. They also may use a light and a magnifying lens to look for signs of a tumor in your eye. If they think you might have eye cancer, they may want to use imaging scans like ultrasound or an MRI to get a closer look. And they may recommend a biopsy -- they'll take a tiny amount of tissue from the growth to look at under a microscope and see if it's cancer.

Depending on the size of the eye cancer, surgery may or may not be recommended.

Treatment: Surgery

If the tumor is small and not growing fast -- and isn't causing many problems for you -- your doctor may just watch it closely. If it gets larger than 10 millimeters around or 3 millimeters tall, they may recommend surgery to take out part or all of the eye, depending on how much of it is affected by the tumor.

Radiation to the eye may lead to dry eyes and vision changes.

Treatment: Radiation

Your doctor may use high beams of energy (usually a type of X-ray) to kill any cancer cells that may still be there - with or without surgery. But this can damage healthy cells, too, and that can make your eyes dry, your eyelashes fall out, or cloud your vision.

Laser therapy may be used to treat certain types of small eye cancers.

Treatment: Laser Therapy

The most common kind of laser treatment, called transpupillary thermotherapy (TTT), focuses a narrow, intense beam of infrared light on your eye to shrink a small tumor. It's used to treat eye melanoma, because those cells absorb the light energy from the laser. It doesn't work with intraocular lymphoma. Laser therapy usually causes fewer side effects than surgery or radiation.

Sources:

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  6. Clinical Photography, Central Manchester University Hospitals NHS Foundation Trust, UK / Science Source
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REFERENCES:

  • American Cancer Society: "Laser Therapy for Eye Cancer," "What Is Retinoblastoma?"
  • American Society Of Clinical Oncology (Cancer.net): "Lacrimal Tumor Guide," "Eyelid Cancer Guide," "Eye Cancer Guide."
  • FDA: "Medical Lasers."
  • NIH: "Retinoblastoma in Adults: a Case Report and Literature Review," "Management of conjunctival malignant melanoma: a review and update," "Lung Cancer and Eye Metastases."
  • Review of Ophthalmology: "Diagnosis & Treatment of Intraocular Lymphoma."
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