Osteoporosis (cont.)

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What are osteoporosis risk factors and causes?

The following are factors that will increase the risk of developing osteoporosis:

  • Female gender
  • Caucasian or Asian race
  • Thin and small body frame
  • Family history of osteoporosis (for example, having a mother with an osteoporotic hip fracture doubles your risk of hip fracture)
  • Personal history of fracture as an adult
  • Cigarette smoking
  • Excessive alcohol consumption
  • Lack of exercise
  • Diet low in calcium
  • Poor nutrition and poor general health
  • Malabsorption (nutrients are not properly absorbed from the gastrointestinal system) from conditions such as celiac sprue
  • Low estrogen levels in women (such as occur in menopause or with early surgical removal of both ovaries)
  • Low testosterone levels in men (hypogonadism)
  • Chemotherapy that can cause early menopause due to its toxic effects on the ovaries
  • Amenorrhea (loss of the menstrual period) in young women is associated with low estrogen and osteoporosis; amenorrhea can occur in women who undergo extremely vigorous exercise training and in women with very low body fat (for example, women with anorexia nervosa)
  • Chronic inflammation, due to chronic diseases such as rheumatoid arthritis or liver diseases
  • Immobility, such as after a stroke, or from any condition that interferes with walking
  • Hyperthyroidism, a condition wherein too much thyroid hormone is produced by the thyroid gland (as in Grave's disease) or is ingested as thyroid hormone medication
  • Hyperparathyroidism is a disease wherein there is excessive parathyroid hormone production by the parathyroid gland, a small gland located near or within the thyroid gland. Normally, parathyroid hormone maintains blood calcium levels by, in part, removing calcium from the bone. In untreated hyperparathyroidism, excessive parathyroid hormone causes too much calcium to be removed from the bone, which can lead to osteoporosis.
  • When vitamin D is lacking, the body cannot absorb adequate amounts of calcium from the diet to prevent osteoporosis. Vitamin D deficiency can result from lack of intestinal absorption of the vitamin such as occurs in celiac sprue and primary biliary cirrhosis.
  • Certain medications can cause osteoporosis. These include long-term use of heparin (a blood thinner), antiseizure medications such as phenytoin (Dilantin) and phenobarbital, and long-term use of oral corticosteroids (such as prednisone).
  • Inherited disorders of connective tissue, including osteogenesis imperfecta, Marfan's syndrome, Ehlers-Danlos syndrome, homocystinuria, and osteoporosis-pseudoglioma syndrome.
Medically Reviewed by a Doctor on 8/29/2014

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Osteoporosis - Symptoms Question: What were your symptoms at the onset of your osteoporosis disease?
Osteoporosis - Treatment Question: What kinds of treatment, including medication or supplements, have you tried for your osteoporosis?
Osteoporosis - Share Your Experience Question: Do you or a relative have osteoporosis? Please share your experience.
Osteoporosis - Risk Factors and Causes Question: Do you have any risk factors for osteoporosis? What are they?
Osteoporosis - Lifestyle Changes Question: What lifestyle changes (diet, exercise, quitting smoking or alcohol), have you made to manage your osteoporosis?
Osteoporosis - Hormone Therapy Experience Question: Have you been prescribed hormone therapy to treat your osteoporosis? What was your experience?
Osteoporosis - Medications Question: What medications have you been prescribed to treat your osteoporosis?
Osteoporosis - Complications Question: Have you had any complications related to your osteoporosis? If so, what were they?