Patient Comments: Erythema Nodosum - Experience

Please describe your experience with erythema nodosum.

Comment from: Allyson, 35-44 Female (Patient) Published: December 12

About eight months after I started taking the pill, I noticed the first knot on my leg. I am a bit clumsy, so I thought it was a bruise. Over the next two months, a few others appeared. I spoke with my OB/GYN and she didn't think it was related to the pill. Sometimes the knots were just bumps, and sometimes they were red and feverish. I work in a hospital lab, and finally one of our pathologists looked at the knots. He immediately told me it was erythema nodosum, a rare side effect of the pill. I got off the pill, and the knots faded. I did have an indentation in my leg where one of the knots was. It lasted more than a year, but it finally went away.

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Comment from: Plumface, 25-34 Female (Patient) Published: December 12

I was diagnosed with EN in early 2001 due to the birth control shot Depo Provera. Birth control pills have been my only trigger until pregnancy. I have had four outbreaks to date. The initial outbreak was in 2001, again when I attempted to take birth control in 2003, another when I was pregnant with my first child in 2006, and now that I am pregnant with my second child in December of 2008. My lumps have stayed below my knees and have not been too painful. I am six months pregnant and worry about the treatments that are out there for me.

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Comment from: Daly, 25-34 Female (Patient) Published: December 04

I had a bad case of erythema nodosum in August of 2007, which lasted about six weeks. I couldn't walk or stand, and the rash affected my feet, legs, and arms.

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Comment from: Kerri, 25-34 Female (Patient) Published: November 14

I am 25 years old and had been on the pill for over a year. I had never experienced an outbreak before, but a bruise suddenly came up and quickly turned into a painful, very large knot. At first I was misdiagnosed with an infection and was given lots of antibiotics. After going to the ER for breathing complications from all the medicine, the doctor looked up my symptoms and told me to get off the pill. Turns out it is somewhat genetic because my mother had the same thing many years earlier, only not as severe. Now I have a dark colored dent on my leg, where the knot used to be.

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Comment from: inpain, 25-34 Female (Patient) Published: November 07

I found out that I had Erythema Nodosum when I was in the forth grade. I am now 29 years old, and I deal with a new break out about every month. I might go a couple months in between, but I rarely get a long break from the painful knots. I very rarely get lucky and only have one or two knots pop up. Most of the time my whole leg is covered (or both legs). I am dealing with a break out that covers from below my knee to above my ankle right now. It used to be worse, to the point that I could barely walk and had to set out of gym class. My teachers thought that I was being abused at home. I wish I know what caused it, or if I could possibly be suffering from one of the related illnesses with out knowing. Unfortunately, my rural community still doesn't know much about the disorder and I can't find a doctor that thinks it's worth looking into. Right now I can't even bare to let my daughter sit on my lap in fear that she will touch my leg.

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Comment from: Just me, 45-54 Female Published: October 30

I was diagnosed with erythema nodosum when I was 18-years-old. I had a very bad attack with quarter size lumps all over my lower and upper legs. At that time (as I am 50 Now ) they did not know much about it. I was treated with prednisone and did not have another attack until I was around 38. Both times I was under very heavy stress and the doctors thought I could possibly be allergic to my own reaction to stress. On and off since then I get very mild attacks when I am under stress where I can feel the slight bumps getting ready to emerge and I try and calm myself. They do not surface anymore but if I rub the area I can feel them. Attacks last approx two weeks.

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Comment from: gina, 45-54 Female (Patient) Published: October 24

I first had erythema nodosum in 1995 after a sore throat and many painful red lumps appeared on my lower legs. I couldn't walk or get any shoes on, I was that swollen. Thirteen years later after another painful sore throat and a week of antibiotics four large red lumps have appeared. I have been diagnosed with erythema nodosum again and am still having to visit doctors and get blood tests done and a chest x-rays.

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